Knowledge Mobility and Entrepreneurial Ecosystem Renewal: A Conceptual Theory of Regional Innovation Regeneration

Authors

  • Arif Efendi Universitas Kepanjen Author

Keywords:

entrepreneurial ecosystems, sustainable entrepreneurial ecosystems, collective value creation, collaborative resource orchestration, stakeholder alignment

Abstract

Entrepreneurial ecosystem research has largely explained how configurations of actors, institutions, and resources support entrepreneurial activity and regional economic performance, yet it remains insufficiently equipped to explain how such ecosystems generate enduring economic, social, and environmental value. Addressing this theoretical gap, this conceptual article develops a middle-range theory of sustainable entrepreneurial ecosystems by identifying collective value creation as the generative mechanism linking ecosystem interaction to sustainability outcomes. The framework is constructed through an integrative synthesis of entrepreneurial ecosystem theory, sustainable entrepreneurship, ecosystem strategy, and relational and stakeholder perspectives, followed by the specification of core constructs, causal mechanisms, boundary conditions, and theoretical propositions. The resulting model explains how collaborative resource orchestration enables heterogeneous actors to co-create multidimensional value, reinforce supportive institutions, and strengthen adaptive resilience. The article advances existing knowledge by shifting attention from ecosystem composition to ecosystem processes and by conceptualizing sustainability as an emergent property of sustained interdependence rather than an additional outcome. The proposed theory offers a coherent basis for empirical testing, contextual refinement, and cumulative research across diverse institutional and regional settings. 

References

Acs, Z. J., Audretsch, D. B., & Feldman, M. P. (1994). R&D spillovers and innovative activity. Managerial and Decision Economics, 15(2), 131–138. https://doi.org/10.1002/mde.4090150205

Acs, Z. J., Braunerhjelm, P., Audretsch, D. B., & Carlsson, B. (2009). The knowledge spillover theory of entrepreneurship. Small Business Economics, 32(1), 15–30. https://doi.org/10.1007/s11187-008-9157-3

Acs, Z. J., Stam, E., Audretsch, D. B., & O’Connor, A. (2017). The lineages of the entrepreneurial ecosystem approach. Small Business Economics, 49(1), 1–10. https://doi.org/10.1007/s11187-017-9864-8

Agrawal, A., Cockburn, I., & McHale, J. (2006). Gone but not forgotten: knowledge flows, labor mobility, and enduring social relationships. Journal of Economic Geography, 6(5), 571–591. https://doi.org/10.1093/jeg/lbl016

Almeida, P., & Kogut, B. (1999). Localization of Knowledge and the Mobility of Engineers in Regional Networks. Management Science, 45(7), 905–917. https://doi.org/10.1287/mnsc.45.7.905

Alvedalen, J., & Boschma, R. (2017). A critical review of entrepreneurial ecosystems research: towards a future research agenda. European Planning Studies, 25(6), 887–903. https://doi.org/10.1080/09654313.2017.1299694

Audretsch, D. B., & Belitski, M. (2021). Frank Knight, uncertainty and knowledge spillover entrepreneurship. Journal of Institutional Economics, 17(6), 1005–1031. https://doi.org/10.1017/S1744137421000527

Audretsch, D. B., & Belitski, M. (2022). The knowledge spillover of innovation. Industrial and Corporate Change, 31(6), 1329–1357. https://doi.org/10.1093/icc/dtac035

Audretsch, D. B., & Belitski, M. (2024). Geography of knowledge collaboration and innovation in Schumpeterian firms. Regional Studies, 58(4), 821–840. https://doi.org/10.1080/00343404.2023.2222137

Audretsch, D. B., Belitski, M., & Guerrero, M. (2023). Sustainable orientation management and institutional quality: Looking into European entrepreneurial innovation ecosystems. Technovation, 124, 102742. https://doi.org/10.1016/j.technovation.2023.102742

Audretsch, D. B., & Keilbach, M. (2008). Resolving the knowledge paradox: Knowledge-spillover entrepreneurship and economic growth. Research Policy, 37(10), 1697–1705. https://doi.org/10.1016/j.respol.2008.08.008

Audretsch, D. B., & Lehmann, E. E. (2005). Does the Knowledge Spillover Theory of Entrepreneurship hold for regions? Research Policy, 34(8), 1191–1202. https://doi.org/10.1016/j.respol.2005.03.012

Audretsch, D. B., & Lehmann, E. E. (2026). A knowledge spillover narrative theory of entrepreneurship. The Journal of Technology Transfer, 51(1), 226–242. https://doi.org/10.1007/s10961-025-10252-4

Audretsch, D., Belitski, M., & Fiedler, A. (2026). The knowledge spillover theory of entrepreneurship and innovation: taking stock and new directions. The Journal of Technology Transfer, 51(4), 2117–2140. https://doi.org/10.1007/s10961-025-10215-9

Balland, P.-A., Boschma, R., Crespo, J., & Rigby, D. L. (2019). Smart specialization policy in the European Union: relatedness, knowledge complexity and regional diversification. Regional Studies, 53(9), 1252–1268. https://doi.org/10.1080/00343404.2018.1437900

Bathelt, H., Malmberg, A., & Maskell, P. (2004). Clusters and knowledge: local buzz, global pipelines and the process of knowledge creation. Progress in Human Geography, 28(1), 31–56. https://doi.org/10.1191/0309132504ph469oa

Boschma, R. (2005). Proximity and Innovation: A Critical Assessment. Regional Studies, 39(1), 61–74. https://doi.org/10.1080/0034340052000320887

Boschma, R. (2015). Towards an Evolutionary Perspective on Regional Resilience. Regional Studies, 49(5), 733–751. https://doi.org/10.1080/00343404.2014.959481

Boschma, R., Coenen, L., Frenken, K., & Truffer, B. (2017). Towards a theory of regional diversification: combining insights from Evolutionary Economic Geography and Transition Studies. Regional Studies, 51(1), 31–45. https://doi.org/10.1080/00343404.2016.1258460

Breschi, S., & Lissoni, F. (2009). Mobility of skilled workers and co-invention networks: an anatomy of localized knowledge flows. Journal of Economic Geography, 9(4), 439–468. https://doi.org/10.1093/jeg/lbp008

Brown, R., & Mason, C. (2017). Looking inside the spiky bits: a critical review and conceptualisation of entrepreneurial ecosystems. Small Business Economics, 49(1), 11–30. https://doi.org/10.1007/s11187-017-9865-7

Chaudhary, S., Kaur, P., Ferraris, A., Bresciani, S., & Dhir, A. (2024). Connecting entrepreneurial ecosystem and innovation. Grasping at straws or hitting a home run? Technovation, 130, 102942. https://doi.org/10.1016/j.technovation.2023.102942

Cohen, W. M., & Levinthal, D. A. (1990). Absorptive Capacity: A New Perspective on Learning and Innovation. Administrative Science Quarterly, 35(1), 128. https://doi.org/10.2307/2393553

Corredoira, R. A., & Rosenkopf, L. (2010). Should auld acquaintance be forgot? the reverse transfer of knowledge through mobility ties. Strategic Management Journal, 31(2), 159–181. https://doi.org/10.1002/smj.803

Cuvero, M., Granados, M. L., Pilkington, A., & Evans, R. (2023). Start‐ups’ use of knowledge spillovers for product innovation: the influence of entrepreneurial ecosystems and virtual platforms. R&D Management, 53(4), 584–602. https://doi.org/10.1111/radm.12567

Fuentes, N., Schmutzler, J., & Vargas, A. M. (2024). Unpacking the multilayered nature of entrepreneurial ecosystems: A conceptual complex adaptive system model. International Journal of Innovation Studies, 8(4), 335–350. https://doi.org/10.1016/j.ijis.2024.08.001

Hassink, R., Isaksen, A., & Trippl, M. (2019). Towards a comprehensive understanding of new regional industrial path development. Regional Studies, 53(11), 1636–1645. https://doi.org/10.1080/00343404.2019.1566704

Hess, S., Wurth, B., Stam, E., Giones, F., Fini, R., Cavallo, A., Wahl, A., Bosma, N., Theodoraki, C., Chabaud, D., Brem, A., & Kuckertz, A. (2025). The future of entrepreneurial ecosystems research: Toward a policy-oriented research agenda. Journal of Business Venturing Insights, 23, e00538. https://doi.org/10.1016/j.jbvi.2025.e00538

Jaffe, A. B., Trajtenberg, M., & Henderson, R. (1993). Geographic Localization of Knowledge Spillovers as Evidenced by Patent Citations. The Quarterly Journal of Economics, 108(3), 577–598. https://doi.org/10.2307/2118401

Leal, M., Leal, C., & Silva, R. (2025). Entrepreneurial Ecosystems and Knowledge Management: Systematic Literature Review and Bibliometric Analysis. Journal of the Knowledge Economy, 17(1), 2920–2967. https://doi.org/10.1007/s13132-025-02730-9

Leendertse, J., Schrijvers, M., & Stam, E. (2022). Measure Twice, Cut Once: Entrepreneurial Ecosystem Metrics. Research Policy, 51(9), 104336. https://doi.org/10.1016/j.respol.2021.104336

Mack, E., & Mayer, H. (2016). The evolutionary dynamics of entrepreneurial ecosystems. Urban Studies, 53(10), 2118–2133. https://doi.org/10.1177/0042098015586547

Martin, R., & Sunley, P. (2006). Path dependence and regional economic evolution. Journal of Economic Geography, 6(4), 395–437. https://doi.org/10.1093/jeg/lbl012

Nooteboom, B., Van Haverbeke, W., Duysters, G., Gilsing, V., & van den Oord, A. (2007). Optimal cognitive distance and absorptive capacity. Research Policy, 36(7), 1016–1034. https://doi.org/10.1016/j.respol.2007.04.003

Rinkinen, S., Konsti-Laakso, S., & Lahikainen, K. (2024). University as an opportunity space enabler in a regional entrepreneurial ecosystem. European Planning Studies, 32(5), 1010–1028. https://doi.org/10.1080/09654313.2023.2246522

Rizvi, S. A. A., Buciuni, G., & Ryan, P. (2025). Multinational enterprise spillover mechanisms in the genesis and evolution of entrepreneurial ecosystems. Small Business Economics, 65(3), 1681–1700. https://doi.org/10.1007/s11187-025-01043-0

Rosenkopf, L., & Almeida, P. (2003). Overcoming Local Search Through Alliances and Mobility. Management Science, 49(6), 751–766. https://doi.org/10.1287/mnsc.49.6.751.16026

Roundy, P. T., Bradshaw, M., & Brockman, B. K. (2018). The emergence of entrepreneurial ecosystems: A complex adaptive systems approach. Journal of Business Research, 86, 1–10. https://doi.org/10.1016/j.jbusres.2018.01.032

Schrijvers, M., Stam, E., & Bosma, N. (2024). Figuring it out: configurations of high-performing entrepreneurial ecosystems in Europe. Regional Studies, 58(5), 1096–1110. https://doi.org/10.1080/00343404.2023.2226727

Song, J., Almeida, P., & Wu, G. (2003). Learning–by–Hiring: When Is Mobility More Likely to Facilitate Interfirm Knowledge Transfer? Management Science, 49(4), 351–365. https://doi.org/10.1287/mnsc.49.4.351.14429

Spigel, B. (2017). The Relational Organization of Entrepreneurial Ecosystems. Entrepreneurship Theory and Practice, 41(1), 49–72. https://doi.org/10.1111/etap.12167

Stam, E. (2015). Entrepreneurial Ecosystems and Regional Policy: A Sympathetic Critique. European Planning Studies, 23(9), 1759–1769. https://doi.org/10.1080/09654313.2015.1061484

Stam, E., & van de Ven, A. (2021). Entrepreneurial ecosystem elements. Small Business Economics, 56(2), 809–832. https://doi.org/10.1007/s11187-019-00270-6

Tödtling, F., & Trippl, M. (2005). One size fits all? Research Policy, 34(8), 1203–1219. https://doi.org/10.1016/j.respol.2005.01.018

Trippl, M., Grillitsch, M., & Isaksen, A. (2018). Exogenous sources of regional industrial change. Progress in Human Geography, 42(5), 687–705. https://doi.org/10.1177/0309132517700982

Wagner, M., Schaltegger, S., Hansen, E. G., & Fichter, K. (2021). University-linked programmes for sustainable entrepreneurship and regional development: how and with what impact? Small Business Economics, 56(3), 1141–1158. https://doi.org/10.1007/s11187-019-00280-4

Wurth, B., Stam, E., & Spigel, B. (2022). Toward an Entrepreneurial Ecosystem Research Program. Entrepreneurship Theory and Practice, 46(3), 729–778. https://doi.org/10.1177/1042258721998948

Downloads

Published

2026-06-02